This title appears in the Scientific Report :
2023
Charakterisierung von Methyltransferasen zur enantioselektiven Synthese von Hexahydropyrrolo[2,3-b]indol basierten Naturstoffen
Charakterisierung von Methyltransferasen zur enantioselektiven Synthese von Hexahydropyrrolo[2,3-b]indol basierten Naturstoffen
The focus of this work is to establish C- and N-methyltransferases for the biocatalytic and stereoselective production of bioactive hexahydropyrrolo[2,3-b]indol alkaloids derived from the natural product physostigmine. Central aspects of the study are the characterization of suitableenzymes, their p...
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Personal Name(s): | Schneider, Pascal (Corresponding author) |
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Contributing Institute: |
Institut für Bioorganische Chemie (HHUD); IBOC |
Imprint: |
Jülich
Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag
2023
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Physical Description: |
x, 315 |
Dissertation Note: |
Dissertation, Heinrich-Heine-Universität Düsseldorf, 2022 |
ISBN: |
978-3-95806-690-8 |
Document Type: |
Book Dissertation / PhD Thesis |
Research Program: |
Biological and environmental resources for sustainable use |
Series Title: |
Bioorganische Chemie an der Heinrich-Heine-Universität im Forschungszentrum Jülich
45 |
Publikationsportal JuSER |
The focus of this work is to establish C- and N-methyltransferases for the biocatalytic and stereoselective production of bioactive hexahydropyrrolo[2,3-b]indol alkaloids derived from the natural product physostigmine. Central aspects of the study are the characterization of suitableenzymes, their preparative use applying a cofactor regeneration system, and investigation of the bioactivity of the hexahydropyrrolo[2,3-b]indoles produced |