This title appears in the Scientific Report :
2023
Please use the identifier:
http://dx.doi.org/10.34734/FZJ-2023-02496 in citations.
Konzeptionierung und Auslegung einer Röntgentarget-Struktur für die Hochleistungs-Strahlentherapie
Konzeptionierung und Auslegung einer Röntgentarget-Struktur für die Hochleistungs-Strahlentherapie
Microbeam radiation therapy offers great potential to revolutionize cancer therapy. To enablethe clinical use of microbeams, new compact devices are needed. The “Line focus x-ray tube” (LFXT)is a promising concept. By introducing the usage of the heat capacity limit, the development of a newx-ray ta...
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Personal Name(s): | Janes, Andre (Corresponding author) |
---|---|
Dimroth, Anton (Thesis advisor) / Rötger, Arne (Thesis advisor) / Butzek, Michael (Thesis advisor) | |
Contributing Institute: |
Zentralinstitut für Technologie; ZEA-1 |
Imprint: |
2022
|
Physical Description: |
91 |
Dissertation Note: |
Masterarbeit, Bergische Universität Wuppertal, 2022 |
DOI: |
10.34734/FZJ-2023-02496 |
Document Type: |
Master Thesis |
Research Program: |
Tumortherapie mit Mikrostrahlen an kompakter Strahlenquelle ohne Topic |
Link: |
OpenAccess |
Publikationsportal JuSER |
Microbeam radiation therapy offers great potential to revolutionize cancer therapy. To enablethe clinical use of microbeams, new compact devices are needed. The “Line focus x-ray tube” (LFXT)is a promising concept. By introducing the usage of the heat capacity limit, the development of a newx-ray target structure for an LFXT will be realized.The presented work pursues the question of how to realize an X-ray target structure with an electronbeam power load of 1.5 MW. For this purpose, different designs and concepts are compared and onthe basis of this comparison, a potential solution is developed. Based on this concept, the componentsof the target are designed. The material selection of the components is carried out with the variousAshby plots, in consideration of specific material requirements. The following dimensioning of thecomponents is based on both analytical calculations and numerical simulations (Ansys). In addition,the well-known problem of carbon diffusion and the associated embrittlement of the focal track isdiscussed.The results of the material selection indicate Carbon fiber reinforced Carbon (CFRC) to be the mostsuitable material for the carrier structure and tungsten-rhenium alloys as the best material for thefocal track. The performed calculations and simulations indicate a CFRC-Structure with a diameterof 660 mm and a quasi-isotropic laminate is a promising solution. A minimum thickness of 1 mm isrecommended for the focal track. This constellation should ensure operation with a 1.5 MW electronbeam and a rotation frequency of 200 Hz for at least 1 second. To reduce the carbon diffusion betweenCFRC and Tungsten common techniques like coating with SiC and Al2O3 and the use of rheniumtungstenmultilayers are discussed. It can be concluded that the use of rhenium-tungsten multilayers isa promising application. This thesis goes on to discuss whether replacing the tungsten interlayers withtantalum provides additional benefits. The results suggest that tantalum can be an effective diffusionbarrier and could increase the lifetime of the focal track. |