This title appears in the Scientific Report :
2023
Please use the identifier:
http://dx.doi.org/10.34734/FZJ-2023-04871 in citations.
Please use the identifier: http://dx.doi.org/10.1093/cercor/bhad351 in citations.
Increased functional connectivity between the auditory cortex and the frontoparietal network compensates for impaired visuomotor transformation after early auditory deprivation
Increased functional connectivity between the auditory cortex and the frontoparietal network compensates for impaired visuomotor transformation after early auditory deprivation
AbstractEarly auditory deprivation leads to a reorganization of large-scale brain networks involving and extending beyond the auditory system. It has been documented that visuomotor transformation is impaired after early deafness, associated with a hyper-crosstalk between the task-critical frontopar...
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Personal Name(s): | Song, Li |
---|---|
Wang, Pengfei / Li, Hui / Weiss-Blankenhorn, Peter / Fink, Gereon R / Zhou, Xiaolin / Chen, Qi (Corresponding author) | |
Contributing Institute: |
Kognitive Neurowissenschaften; INM-3 |
Published in: | Cerebral cortex, 33 (2023) 22, S. 11126 - 11145 |
Imprint: |
Oxford
Oxford Univ. Press
2023
|
DOI: |
10.34734/FZJ-2023-04871 |
DOI: |
10.1093/cercor/bhad351 |
Document Type: |
Journal Article |
Research Program: |
Multilevel Brain Organization and Variability |
Link: |
Restricted Published on 2023-10-09. Available in OpenAccess from 2024-10-09. Published on 2023-10-09. Available in OpenAccess from 2024-10-09. |
Publikationsportal JuSER |
Please use the identifier: http://dx.doi.org/10.1093/cercor/bhad351 in citations.
AbstractEarly auditory deprivation leads to a reorganization of large-scale brain networks involving and extending beyond the auditory system. It has been documented that visuomotor transformation is impaired after early deafness, associated with a hyper-crosstalk between the task-critical frontoparietal network and the default-mode network. However, it remains unknown whether and how the reorganized large-scale brain networks involving the auditory cortex contribute to impaired visuomotor transformation after early deafness. Here, we asked deaf and early hard of hearing participants and normal hearing controls to judge the spatial location of a visual target. Compared with normal hearing controls, the superior temporal gyrus showed significantly increased functional connectivity with the frontoparietal network and the default-mode network in deaf and early hard of hearing participants, specifically during egocentric judgments. However, increased superior temporal gyrus-frontoparietal network and superior temporal gyrus-default-mode network coupling showed antagonistic effects on egocentric judgments. In deaf and early hard of hearing participants, increased superior temporal gyrus-frontoparietal network connectivity was associated with improved egocentric judgments, whereas increased superior temporal gyrus-default-mode network connectivity was associated with deteriorated performance in the egocentric task. Therefore, the data suggest that the auditory cortex exhibits compensatory neuroplasticity (i.e. increased functional connectivity with the task-critical frontoparietal network) to mitigate impaired visuomotor transformation after early auditory deprivation.Keywords: connectomics; deaf and early hard of hearing; modularity; neural plasticity; superior temporal gyrus. |