This title appears in the Scientific Report :
2013
Please use the identifier:
http://dx.doi.org/10.1063/1.4820447 in citations.
Please use the identifier: http://hdl.handle.net/2128/5717 in citations.
Superparamagnetic nanoparticle detection using second harmonic of magnetization response
Superparamagnetic nanoparticle detection using second harmonic of magnetization response
We introduce a method to improve the detection sensitivity for the magnetization M of superparamagnetic nanoparticles (MNP). The M response of MNP to an applied magnetic field H (M–H characteristics) could be divided into a linear region and a saturation region, which are separated at a transition p...
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Personal Name(s): | Zhang, Yi (Corresponding author) |
---|---|
Murata, Hayaki / Hatsukade, Yoshimi / Tanaka, Saburo | |
Contributing Institute: |
JARA-FIT; JARA-FIT Bioelektronik; ICS-8 Bioelektronik; PGI-8 |
Published in: | Review of scientific instruments, 84 (2013) 9, S. 094702 - |
Imprint: |
[S.l.]
American Institute of Physics
2013
|
DOI: |
10.1063/1.4820447 |
Document Type: |
Journal Article |
Research Program: |
Physics of the Cell Sensorics and bioinspired systems |
Link: |
OpenAccess |
Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/5717 in citations.
We introduce a method to improve the detection sensitivity for the magnetization M of superparamagnetic nanoparticles (MNP). The M response of MNP to an applied magnetic field H (M–H characteristics) could be divided into a linear region and a saturation region, which are separated at a transition point H k. When applying an excitation magnetic field (H ac ) with a frequency ω0 and an additional dc bias field H dc = H k, the second harmonic of M reaches the maximum due to the nonlinearity of the M–H characteristics. It is stronger than any other harmonics and responsible for small H ac without a threshold. The second harmonic selected as the readout criterion for M response of MNP is systematically analyzed and experimentally proven. |