This title appears in the Scientific Report :
2014
Please use the identifier:
http://dx.doi.org/10.1044/2014_JSLHR-S-13-0155 in citations.
The Effect of Deep Brain Stimulation on the Speech Motor System
The Effect of Deep Brain Stimulation on the Speech Motor System
Purpose: Chronic deep brain stimulation of the nucleus ventralis intermedius is an effective treatment for individuals with medication-resistant essential tremor. However, these individuals report that stimulation has a deleterious effect on their speech. The present study investigates one important...
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Personal Name(s): | Mücke, D. (Corresponding author) |
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Becker, J. / Barbe, Michael / Meister, I. / Liebhart, L. / Röttger, T. B. / Dembek, T. / Timmermann, L. / Grice, M. | |
Contributing Institute: |
Kognitive Neurowissenschaften; INM-3 |
Published in: | Journal of speech, language, and hearing research, 57 (2014) S. 1206-1218 |
Imprint: |
Rockville, Md.
American Speech-Language-Hearing Association
2014
|
DOI: |
10.1044/2014_JSLHR-S-13-0155 |
Document Type: |
Journal Article |
Research Program: |
(Dys-)function and Plasticity Pathophysiological Mechanisms of Neurological and Psychiatric Diseases |
Publikationsportal JuSER |
Purpose: Chronic deep brain stimulation of the nucleus ventralis intermedius is an effective treatment for individuals with medication-resistant essential tremor. However, these individuals report that stimulation has a deleterious effect on their speech. The present study investigates one important factor leading to these effects: the coordination of oral and glottal articulation.Method: Sixteen native-speaking German adults with essential tremor, between 26 and 86 years old, with and without chronic deep brain stimulation of the nucleus ventralis intermedius and 12 healthy, age-matched subjects were recorded performing a fast syllable repetition task (/papapa/, /tatata/, /kakaka/). Syllable duration and voicing-to-syllable ratio as well as parameters related directly to consonant production, voicing during constriction, and frication during constriction were measured.Results: Voicing during constriction was greater in subjects with essential tremor than in controls, indicating a perseveration of voicing into the voiceless consonant. Stimulation led to fewer voiceless intervals (voicing-to-syllable ratio), indicating a reduced degree of glottal abduction during the entire syllable cycle. Stimulation also induced incomplete oral closures (frication during constriction), indicating imprecise oral articulation.Conclusion: The detrimental effect of stimulation on the speech motor system can be quantified using acoustic measures at the subsyllabic level. |