This title appears in the Scientific Report : 2014 

Young Adults with Dyskinetic Cerebral Palsy Improve Subjectively on Pallidal Stimulation, but not in Formal Dystonia, Gait, Speech and Swallowing Testing
Koy, A. (Corresponding author)
Pauls, A. / Flossdorf, P. / Becker, J. / Schönau, E. / Maarouf, M. / Liebig, T. / Fricke, O. / Fink, G. R. / Timmermann, L.
Kognitive Neurowissenschaften; INM-3
Neuropediatrics, 44 (2014) 2, S. FV15_07
Stuttgart [u.a.] Thieme 2013
Journal Article
(Dys-)function and Plasticity
Pathophysiological Mechanisms of Neurological and Psychiatric Diseases
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Cerebral palsy (CP) is a common cause for secondary dystonia. Pharmacological treatment is often unsatisfactory or side effects are dose limiting. There is only limited data about the effect of deep brain stimulation (DBS) in patients with dyskinetic CP. A meta-analysis on the percentage change in the Burke-Fahn-Marsden dystonia rating scale (BFMDRS) revealed an improvement of 23% in patients with dyskinetic CP and DBS. In this study, we assessed the effect of pallidal DBS on dystonia, gait, speech, swallowing, and subjective perception of symptoms.