This title appears in the Scientific Report :
2011
Please use the identifier:
http://dx.doi.org/10.1093/cercor/bhr020 in citations.
Saccade-Related Modulations of Neuronal Excitability Support Synchrony of Visually Elicited Spikes
Saccade-Related Modulations of Neuronal Excitability Support Synchrony of Visually Elicited Spikes
During natural vision, primates perform frequent saccadic eye movements, allowing only a narrow time window for processing the visual information at each location. Individual neurons may contribute only with a few spikes to the visual processing during each fixation, suggesting precise spike timing...
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Personal Name(s): | Ito, J. |
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Maldonado, P. / Singer, W. / Grün, S. | |
Contributing Institute: |
Computational and Systems Neuroscience; INM-6 |
Published in: | Cerebral cortex, 21 (2011) S. 2482 - 2497 |
Imprint: |
Oxford
Oxford Univ. Press
2011
|
Physical Description: |
2482 - 2497 |
PubMed ID: |
21459839 |
DOI: |
10.1093/cercor/bhr020 |
Document Type: |
Journal Article |
Research Program: |
Pathophysiological Mechanisms of Neurological and Psychiatric Diseases Neurowissenschaften |
Series Title: |
Cerebral Cortex
21 |
Subject (ZB): | |
Publikationsportal JuSER |
During natural vision, primates perform frequent saccadic eye movements, allowing only a narrow time window for processing the visual information at each location. Individual neurons may contribute only with a few spikes to the visual processing during each fixation, suggesting precise spike timing as a relevant mechanism for information processing. We recently found in V1 of monkeys freely viewing natural images, that fixation-related spike synchronization occurs at the early phase of the rate response after fixation-onset, suggesting a specific role of the first response spikes in V1. Here, we show that there are strong local field potential (LFP) modulations locked to the onset of saccades, which continue into the successive fixation periods. Visually induced spikes, in particular the first spikes after the onset of a fixation, are locked to a specific epoch of the LFP modulation. We suggest that the modulation of neural excitability, which is reflected by the saccade-related LFP changes, serves as a corollary signal enabling precise timing of spikes in V1 and thereby providing a mechanism for spike synchronization. |