This title appears in the Scientific Report :
2014
Please use the identifier:
http://dx.doi.org/10.1155/2014/812973 in citations.
Please use the identifier: http://hdl.handle.net/2128/7839 in citations.
18 F-Labelled Intermediates for Radiosynthesis by Modular Build-Up Reactions: Newer Developments
18 F-Labelled Intermediates for Radiosynthesis by Modular Build-Up Reactions: Newer Developments
This brief review gives an overview of newer developments in 18F-chemistry with the focus on small 18F-labelled molecules as intermediates for modular build-up syntheses. The short half-life (<2 h) of the radionuclide requires efficient syntheses of these intermediates considering that multistep...
Saved in:
Personal Name(s): | Ermert, Johannes (Corresponding Author) |
---|---|
Contributing Institute: |
Nuklearchemie; INM-5 |
Published in: | BioMed research international, 2014 (2014) ID 812973, S. 1 - 15 |
Imprint: |
New York [u.a.]
Hindawi
2014
|
DOI: |
10.1155/2014/812973 |
Document Type: |
Journal Article |
Research Program: |
Neuroimaging Pathophysiological Mechanisms of Neurological and Psychiatric Diseases |
Link: |
OpenAccess |
Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/7839 in citations.
This brief review gives an overview of newer developments in 18F-chemistry with the focus on small 18F-labelled molecules as intermediates for modular build-up syntheses. The short half-life (<2 h) of the radionuclide requires efficient syntheses of these intermediates considering that multistep syntheses are often time consuming and characterized by a loss of yield in each reaction step. Recent examples of improved synthesis of 18F-labelled intermediates show new possibilities for no-carrier-added ring-fluorinated arenes, novel intermediates for tri[18F]fluoromethylation reactions, and 18F-fluorovinylation methods |