This title appears in the Scientific Report :
2011
Please use the identifier:
http://dx.doi.org/10.3233/NRE-2011-0663 in citations.
Stochastic resonance therapy in Parkinson's disease
Stochastic resonance therapy in Parkinson's disease
To test the effects of stochastic whole body vibration (WBV) we performed a double-blind randomized controlled study.Patients were allocated either to the experimental or sham group. The experimental group received 5 cycles of stochastic WBV on three days, each cycle consisting of 5 stimulus trains...
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Personal Name(s): | Kaut, O. |
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Allert, N. / Coch, C. / Paus, S. / Grezeska, A. / Minnerop, M. / Wüllner, U. | |
Contributing Institute: |
Strukturelle und funktionelle Organisation des Gehirns; INM-1 |
Published in: | Neurorehabilitation, 28 (2011) S. 353 - 358 |
Imprint: |
Amsterdam
IOS Press
2011
|
Physical Description: |
353 - 358 |
DOI: |
10.3233/NRE-2011-0663 |
PubMed ID: |
21725168 |
Document Type: |
Journal Article |
Research Program: |
Connectivity and Activity Funktion und Dysfunktion des Nervensystems |
Series Title: |
NeuroRehabilitation
28 |
Subject (ZB): | |
Publikationsportal JuSER |
To test the effects of stochastic whole body vibration (WBV) we performed a double-blind randomized controlled study.Patients were allocated either to the experimental or sham group. The experimental group received 5 cycles of stochastic WBV on three days, each cycle consisting of 5 stimulus trains of 60 seconds duration (frequency 6.5 Hz) and 60 seconds resting time between stimuli. Patients allocated to the control group received a sham treatment with 1 Hz. Unified Parkinson's Disease Rating Scale, part III (UPDRSIII) was performed after treatment at baseline, after the first series on day 1 and on day 5.The reduction of subscores included in UPDRS III relative to baseline served as primary outcome measure. After the five-day course bradykinesia was improved in 14 of 18 patients (77.8%) and postural stability in 8 of 18 (44.4%). Speech and facial expression remained unchanged in both groups. Tremor (p=0.027) and postural stability (p=0.048) showed a reduction also, but did not reached level of significance (p < 0.01); UPDRSIII sum score was improved by 26.7%.Stochastic whole body vibration may offer a supplementation to canonical physical treatments of PD motor symptoms. |