This title appears in the Scientific Report :
2015
Please use the identifier:
http://dx.doi.org/10.1039/C5SM00678C in citations.
Please use the identifier: http://hdl.handle.net/2128/22851 in citations.
Ultrafiltration modeling of non-ionic microgels
Ultrafiltration modeling of non-ionic microgels
Membrane ultrafiltration (UF) is a pressure driven process allowing for the separation and enrichment of protein solutions and dispersions of nanosized microgel particles. The permeate flux and the near-membrane concentration-polarization (CP) layer in this process is determined by advective-diffusi...
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Personal Name(s): | Roa, Rafael (Corresponding Author) |
---|---|
Zholkovskiy, Emiliy K. / Naegele, Gerhard | |
Contributing Institute: |
Weiche Materie; ICS-3 |
Published in: | Soft matter, 11 (2015) 20, S. 4106-4122 |
Imprint: |
London
Royal Soc. of Chemistry
2015
|
DOI: |
10.1039/C5SM00678C |
PubMed ID: |
25921331 |
Document Type: |
Journal Article |
Research Program: |
Kontinuierliche Trennung und Aufkonzentrierung von Mikrogelen (B06) Functional Macromolecules and Complexes |
Link: |
Restricted OpenAccess Restricted |
Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/22851 in citations.
Membrane ultrafiltration (UF) is a pressure driven process allowing for the separation and enrichment of protein solutions and dispersions of nanosized microgel particles. The permeate flux and the near-membrane concentration-polarization (CP) layer in this process is determined by advective-diffusive dispersion transport and the interplay of applied and osmotic transmembrane pressure contributions. The UF performance is thus strongly dependent on the membrane properties, the hydrodynamic structure of the Brownian particles, their direct and hydrodynamic interactions, and the boundary conditions. We present a macroscopic description of cross-flow UF of non-ionic microgels modeled as solvent-permeable spheres. Our filtration model involves recently derived semi-analytic expressions for the concentration-dependent collective diffusion coefficient and viscosity of permeable particle dispersions [Riest et al., Soft Matter, 2015, 11, 2821]. These expressions have been well tested against computer simulation and experimental results. We analyze the CP layer properties and the permeate flux at different operating conditions and discuss various filtration process efficiency and cost indicators. Our results show that the proper specification of the concentration-dependent transport coefficients is important for reliable filtration process predictions. We also show that the solvent permeability of microgels is an essential ingredient to the UF modeling. The particle permeability lowers the particle concentration at the membrane surface, thus increasing the permeate flux. |