This title appears in the Scientific Report :
2015
Please use the identifier:
http://dx.doi.org/10.1007/s00259-014-2760-4 in citations.
Thyroid nodules with indeterminate cytology: molecular imaging with $^{99m}$ Tc-methoxyisobutylisonitrile (MIBI) is more cost-effective than the Afirma® gene expression classifier
Thyroid nodules with indeterminate cytology: molecular imaging with $^{99m}$ Tc-methoxyisobutylisonitrile (MIBI) is more cost-effective than the Afirma® gene expression classifier
PurposeTo compare the cost-effectiveness of 99mTc-methoxyisobutylisonitrile (MIBI) thyroid scintigraphy and the Afirma® gene expression classifier for the assessment of cytologically indeterminate thyroid nodules.MethodsA decision tree model was used. Costs were calculated from the perspective of th...
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Personal Name(s): | Heinzel, Alexander (Corresponding Author) |
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Müller, Dirk / Behrendt, Florian F. / Giovanella, Luca / Mottaghy, Felix M. / Verburg, Frederik A. | |
Contributing Institute: |
Physik der Medizinischen Bildgebung; INM-4 JARA-BRAIN; JARA-BRAIN |
Published in: | European journal of nuclear medicine and molecular imaging, 41 (2014) 8, S. 1497 - 1500 |
Imprint: |
Heidelberg [u.a.]
Springer-Verl.
2014
|
DOI: |
10.1007/s00259-014-2760-4 |
Document Type: |
Journal Article |
Research Program: |
Imaging the Living Brain |
Publikationsportal JuSER |
PurposeTo compare the cost-effectiveness of 99mTc-methoxyisobutylisonitrile (MIBI) thyroid scintigraphy and the Afirma® gene expression classifier for the assessment of cytologically indeterminate thyroid nodules.MethodsA decision tree model was used. Costs were calculated from the perspective of the German health insurance system. The robustness of the results was assessed with probabilistic sensitivity analyses using a Monte Carlo simulation.ResultsLife expectancy was 34.3 years (estimated costs per patient €1,459 – €2,224) for the MIBI scan and 34.1 years (estimated costs €3,560 – €4,071) for the molecular test. These results were confirmed by the Monte Carlo simulation.ConclusionMIBI thyroid scintigraphy is more cost-effective than the gene expression classifier |