This title appears in the Scientific Report :
2015
Please use the identifier:
http://dx.doi.org/10.1002/pssa.201532053 in citations.
Fabrication of biocompatible lab-on-chip devices for biomedical applications by means of a 3D-printing process
Fabrication of biocompatible lab-on-chip devices for biomedical applications by means of a 3D-printing process
A new microfluidic assembly method for semiconductor-based biosensors using 3D-printing technologies was proposed for a rapid and cost-efficient design of new sensor systems. The microfluidic unit is designed and printed by a 3D-printer in just a few hours and assembled on a light-addressable potent...
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Personal Name(s): | Takenaga, S. |
---|---|
Schneider, B. / Erbay, E. / Biselli, M. / Schnitzler, Th. / Schöning, M. J. / Wagner, T. (Corresponding author) | |
Contributing Institute: |
Bioelektronik; PGI-8 |
Published in: | Physica status solidi / A, 212 (2015) 6, S. 1347 - 1352 |
Imprint: |
2015
|
DOI: |
10.1002/pssa.201532053 |
Document Type: |
Journal Article |
Research Program: |
Controlling Configuration-Based Phenomena |
Publikationsportal JuSER |
A new microfluidic assembly method for semiconductor-based biosensors using 3D-printing technologies was proposed for a rapid and cost-efficient design of new sensor systems. The microfluidic unit is designed and printed by a 3D-printer in just a few hours and assembled on a light-addressable potentiometric sensor (LAPS) chip using a photo resin. The cell growth curves obtained from culturing cells within microfluidics-based LAPS systems were compared with cell growth curves in cell culture flasks to examine biocompatibility of the 3D-printed chips. Furthermore, an optimal cell culturing within microfluidics-based LAPS chips was achieved by adjusting the fetal calf serum concentrations of the cell culture medium, an important factor for the cell proliferation. |