This title appears in the Scientific Report :
2009
Please use the identifier:
http://dx.doi.org/10.1093/brain/awn304 in citations.
Grapheme-colour synasthetes show increased grey matter volumes of parietal and fusiform cortex
Grapheme-colour synasthetes show increased grey matter volumes of parietal and fusiform cortex
In synaesthesia, stimulation of a sensory modality triggers abnormal additional perceptions. Voxel-based morphometry (VBM) was used in 18 grapheme-colour synaesthetes to investigate the neuro-anatomical basis of their abnormal perceptions. More specifically, we tested the hypothesis that in synaesth...
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Personal Name(s): | Weiss, P. H. |
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Fink, G. R. | |
Contributing Institute: |
Kognitive Neurowissenschaften; INM-3 |
Published in: | Brain, 132 (2009) S. 65 - 70 |
Imprint: |
Oxford
Oxford Univ. Press
2009
|
Physical Description: |
65 - 70 |
PubMed ID: |
19028762 |
DOI: |
10.1093/brain/awn304 |
Document Type: |
Journal Article |
Research Program: |
Funktion und Dysfunktion des Nervensystems |
Series Title: |
Brain
132 |
Subject (ZB): | |
Publikationsportal JuSER |
In synaesthesia, stimulation of a sensory modality triggers abnormal additional perceptions. Voxel-based morphometry (VBM) was used in 18 grapheme-colour synaesthetes to investigate the neuro-anatomical basis of their abnormal perceptions. More specifically, we tested the hypothesis that in synaesthesia altered connectivity in temporo-occipital and parietal areas may be associated with grey matter (GM) changes. The data reveal increased GM volumes in fusiform and intraparietal cortices. These findings are consistent with the two-stage model of grapheme-colour synaesthesia implying cross-activation at the level of the fusiform gyrus (FG) and 'hyperbinding' at the level of the parietal cortex. The observed structural differences in grapheme-colour synaesthetes with abnormal additional perceptions may also shed some light on the neural bases of abnormal perceptions in neurological and psychiatric disorders. |