This title appears in the Scientific Report :
2008
Please use the identifier:
http://dx.doi.org/10.1093/cercor/bhm224 in citations.
The Central Sulcus: an Observer-Independent Characterization of Sulcal Landmarks and Depth Asymmetry
The Central Sulcus: an Observer-Independent Characterization of Sulcal Landmarks and Depth Asymmetry
Studies of the central sulcus (CS) often use observer-dependent procedures to assess CS morphology and sulcal landmarks. Here, we applied a novel method combining automated sulcus reconstruction, surface parameterization, and an observer-independent depth measurement to study the CS. This facilitate...
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Personal Name(s): | Cykowski, M.D. |
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Coulon, O. / Kochunov, P.V. / Amunts, K. / Lancaster, J.L. / Laird, A.R. / Glahn, D.C. / Fox, P.T. | |
Contributing Institute: |
Institut für Neurowissenschaften und Biophysik - Medizin; INB-3 JARA-BRAIN; JARA-BRAIN |
Published in: | Cerebral cortex, 18 (2008) S. 1999 - 2009 |
Imprint: |
Oxford
Oxford Univ. Press
2008
|
Physical Description: |
1999 - 2009 |
DOI: |
10.1093/cercor/bhm224 |
PubMed ID: |
18071195 |
Document Type: |
Journal Article |
Research Program: |
Funktion und Dysfunktion des Nervensystems |
Series Title: |
Cerebral Cortex
18 |
Subject (ZB): | |
Publikationsportal JuSER |
Studies of the central sulcus (CS) often use observer-dependent procedures to assess CS morphology and sulcal landmarks. Here, we applied a novel method combining automated sulcus reconstruction, surface parameterization, and an observer-independent depth measurement to study the CS. This facilitated the quantitative assessment of the spatial position and intersubject variability of several sulcal landmarks. Sulcal depth profiles also allowed us to develop an algorithm for the clear identification of several landmarks, including the pli de passage fronto-pariétal moyen (PPFM), first described by Broca. Using this algorithm, the PPFM was identified in the majority of sulci, but exhibited limited spatial variability. This appears to support Cunningham's theory that this landmark may be a developmental remnant, and may argue against its role as a guide to the more variable somatotopic hand area. Sulcal depth profiles were also utilized to assess the influence of sex, handedness, and age on CS morphology. These profiles revealed leftward depth asymmetry in the superior extent of the CS of male subjects and near the midpoint of the CS in female subjects. Age correlations were performed for these asymmetries, and a significant correlation was seen only in the male subgroup. |