This title appears in the Scientific Report :
2005
Please use the identifier:
http://dx.doi.org/10.1002/hbm.20198 in citations.
Age-related morphology trends of cortical sulci
Age-related morphology trends of cortical sulci
The age-related trends of the width and the depth of major cortical sulci were studied in normal adults. Ninety healthy subjects (47 males, 43 females) age 20-82 years were evaluated. Measurements of average sulcal width and depth in 14 prominent sulcal structures per hemisphere were performed with...
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Personal Name(s): | Kochunov, P. |
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Mangin, Z. M. / Coyle, T. / Lancaster, J. / Thompson, P. / Riviere, D. / Cointepas, Y. / Regis, J. / Schlösser, A. / Royall, D. R. / Zilles, K. / Mazziotta, J. / Toga, A. / Fox, P. T. | |
Contributing Institute: |
Institut für Medizin; IME |
Published in: | Human brain mapping, 26 (2005) S. 210 - 220 |
Imprint: |
New York, NY
Wiley-Liss
2005
|
Physical Description: |
210 - 220 |
PubMed ID: |
16161162 |
DOI: |
10.1002/hbm.20198 |
Document Type: |
Journal Article |
Research Program: |
Neurowissenschaften |
Series Title: |
Human Brain Mapping
26 |
Subject (ZB): | |
Publikationsportal JuSER |
The age-related trends of the width and the depth of major cortical sulci were studied in normal adults. Ninety healthy subjects (47 males, 43 females) age 20-82 years were evaluated. Measurements of average sulcal width and depth in 14 prominent sulcal structures per hemisphere were performed with high-resolution anatomical MRI. The average sulcal width increased at a rate of about 0.7 mm/decade, while the average sulcal depth decreased at a rate of about 0.4 mm/decade. Sulcal age-related trends were found to be highly influenced by gender in the superior temporal, collateral, and cingulate sulci (P < 0.05), with males showing more pronounced age-related change in sulcal width than females. Sulcal structures located in multimodal cortical areas showed more profound age-related changes than sulcal structures in unimodal cortical areas (P < 0.05). |