This title appears in the Scientific Report :
2006
Please use the identifier:
http://dx.doi.org/10.1529/biophysj.105.077099 in citations.
Theoretical Analysis of Single-Molecule Force Spectroscopy Experiments: Heterogeneity of Chemical Bonds
Theoretical Analysis of Single-Molecule Force Spectroscopy Experiments: Heterogeneity of Chemical Bonds
We show that the standard theoretical framework in single-molecule force spectroscopy has to be extended to consistently describe the experimental findings. The basic amendment is to take into account heterogeneity of the chemical bonds via random variations of the force-dependent dissociation rates...
Saved in:
Personal Name(s): | Raible, M. |
---|---|
Evstigneev, M. / Bartels, F. W. / Eckel, R. / Nguyen-Duong, M. / Merkel, R. / Ros, R. / Anselmetti, D. / Reimann, P. | |
Contributing Institute: |
Biologische Schichten; ISG-4 |
Published in: | Biophysical journal, 90 (2006) S. 3851 - 3864 |
Imprint: |
New York, NY
Rockefeller Univ. Press
2006
|
Physical Description: |
3851 - 3864 |
DOI: |
10.1529/biophysj.105.077099 |
PubMed ID: |
16513778 |
Document Type: |
Journal Article |
Research Program: |
Kondensierte Materie |
Series Title: |
Biophysical Journal
90 |
Subject (ZB): | |
Publikationsportal JuSER |
We show that the standard theoretical framework in single-molecule force spectroscopy has to be extended to consistently describe the experimental findings. The basic amendment is to take into account heterogeneity of the chemical bonds via random variations of the force-dependent dissociation rates. This results in a very good agreement between theory and rupture data from several different experiments. |