This title appears in the Scientific Report :
2006
Detection of new two-membrane structures in native mitochondria by the method of small-angle scattering of neutrons
Detection of new two-membrane structures in native mitochondria by the method of small-angle scattering of neutrons
The structure of mitochondrial cristas has been studied for the first time by the method of small-angle scattering of thermal neutrons. Experiments were performed on intact functioning rat liver mitochondria. Mitochondrial cristas are usually considered as folds of the internal membrane with arbitra...
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Personal Name(s): | Murugova, T. N. |
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Gordeliy, V. I. / Kuklin, A. I. / Kovalev, J. S. / Iurkov, V. I. / Nürenberg, A. / Islamov, A. Kh. / Iaguzhinskiy, L. S. | |
Contributing Institute: |
Biologische Strukturforschung; IBI-2 |
Published in: | Biofizika, 51 (2006) S. 1001 - 1007 |
Imprint: |
Moskva
Nauka
2006
|
Physical Description: |
1001 - 1007 |
Document Type: |
Journal Article |
Research Program: |
Funktion und Dysfunktion des Nervensystems |
Series Title: |
Biofizika
51 |
Subject (ZB): | |
Publikationsportal JuSER |
The structure of mitochondrial cristas has been studied for the first time by the method of small-angle scattering of thermal neutrons. Experiments were performed on intact functioning rat liver mitochondria. Mitochondrial cristas are usually considered as folds of the internal membrane with arbitrary nonfixed intermembrane distances. It was shown that, under particular conditions, during low-amplitude swelling of mitochondria, cristas are transformed to bimembrane structures, with the distance between the central planes of membranes of 190 E. It was found that the formation of bimembrane structures and their structural parameters do not depend on the method of induction of swelling, by placing the mitochondria into a hypotonic medium or by the opening of nonspecific pores. |