This title appears in the Scientific Report :
2008
Please use the identifier:
http://dx.doi.org/10.1063/1.2907718 in citations.
Please use the identifier: http://hdl.handle.net/2128/19028 in citations.
The Alzheimer's beta amyloid (A beta {1-39} monomer in an implicit solvent
The Alzheimer's beta amyloid (A beta {1-39} monomer in an implicit solvent
Results from replica-exchange and regular room temperature molecular dynamics simulations of the Alzheimer's beta amyloid (Abeta(1-39)) monomer in an implicit solvent are reported. Our data indicate that at room temperature, the monomer assumes random-coil and soluble conformations. No beta con...
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Personal Name(s): | Anand, P. |
---|---|
Nandel, N. S. / Hansmann, U. H. E. | |
Contributing Institute: |
John von Neumann - Institut für Computing; NIC |
Published in: | The @journal of chemical physics, 128 (2008) S. 165102 |
Imprint: |
Melville, NY
American Institute of Physics
2008
|
Physical Description: |
165102 |
PubMed ID: |
18447506 |
DOI: |
10.1063/1.2907718 |
Document Type: |
Journal Article |
Research Program: |
Scientific Computing |
Series Title: |
Journal of Chemical Physics
128 |
Subject (ZB): | |
Link: |
Get full text OpenAccess OpenAccess |
Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/19028 in citations.
Results from replica-exchange and regular room temperature molecular dynamics simulations of the Alzheimer's beta amyloid (Abeta(1-39)) monomer in an implicit solvent are reported. Our data indicate that at room temperature, the monomer assumes random-coil and soluble conformations. No beta content is observed which therefore seems to be a product of oligomerization and aggregation of monomers. |