This title appears in the Scientific Report :
2016
Please use the identifier:
http://dx.doi.org/10.1016/j.polymer.2016.07.059 in citations.
Structure and dynamics of single-chain nano-particles in solution
Structure and dynamics of single-chain nano-particles in solution
By means of intramolecular folding/collapse of individual polymer chains (precursors), ultra-small soft nano-objects called single-chain nano-particles (SCNPs) can be synthesized. Here we present a combination of scattering techniques [small angle X-Ray and neutron scattering (SAXS and SANS), neutro...
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Personal Name(s): | Arbe, A. (Corresponding author) |
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Pomposo, J. A. / Moreno, A. J. / LoVerso, F. / González-Burgos, M. / Asenjo-Sanz, I. / Iturrospe, A. / Radulescu, A. / Ivanova, O. / Colmenero, J. | |
Contributing Institute: |
Neutronenstreuung; JCNS-1 JCNS-FRM-II; JCNS-FRM-II |
Published in: | Polymer, 105 (2016) S. 532–544 |
Imprint: |
Oxford
Elsevier Science
2016
|
DOI: |
10.1016/j.polymer.2016.07.059 |
Document Type: |
Journal Article |
Research Program: |
Jülich Centre for Neutron Research (JCNS) FRM II / MLZ |
Subject (ZB): | |
Publikationsportal JuSER |
By means of intramolecular folding/collapse of individual polymer chains (precursors), ultra-small soft nano-objects called single-chain nano-particles (SCNPs) can be synthesized. Here we present a combination of scattering techniques [small angle X-Ray and neutron scattering (SAXS and SANS), neutron spin echo (NSE) and dynamic light scattering (DLS)] to investigate the structure and dynamics of SCNPs in solution and their linear precursors as reference. Coarse-grained molecular dynamics (MD) simulations have also been carried out to complement this study. The application of SANS and SAXS has proved the compaction of the macromolecules upon creation of internal cross-links. However, the SCNPs obtained by different routes exhibit a far from globular topology in good solvent. Regarding the dynamics, we report on the first experimental investigation of the dynamic structure factor of SCNPs in solution. It reveals a clear impact of internal cross-links through (i) a reduction of the translational diffusion coefficient and (ii) an important slowing down of the internal modes. The data have been analyzed in terms of theoretical approximations based on the Zimm model. Both, structurally and dynamically, SCNPs show striking resemblances with intrinsically disordered proteins: similar scaling properties reflecting sparse morphologies and an extremely high internal friction. |