This title appears in the Scientific Report :
2017
Please use the identifier:
http://dx.doi.org/10.1038/srep39682 in citations.
Please use the identifier: http://hdl.handle.net/2128/13714 in citations.
Dendritic and Axonal Propagation Delays Determine Emergent Structures of Neuronal Networks with Plastic Synapses
Dendritic and Axonal Propagation Delays Determine Emergent Structures of Neuronal Networks with Plastic Synapses
Spike-timing-dependent plasticity (STDP) modifies synaptic strengths based on the relative timing of pre- and postsynaptic spikes. The temporal order of spikes turned out to be crucial. We here take into account how propagation delays, composed of dendritic and axonal delay times, may affect the tem...
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Personal Name(s): | Madadi Asl, Mojtaba (Corresponding author) |
---|---|
Valizadeh, Alireza / Tass, Peter A. | |
Contributing Institute: |
Gehirn & Verhalten; INM-7 |
Published in: | Scientific reports, 7 (2017) S. 39682 |
Imprint: |
2017
|
DOI: |
10.1038/srep39682 |
PubMed ID: |
28045109 |
Document Type: |
Journal Article |
Research Program: |
Addenda Connectivity and Activity |
Link: |
OpenAccess OpenAccess |
Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/13714 in citations.
Spike-timing-dependent plasticity (STDP) modifies synaptic strengths based on the relative timing of pre- and postsynaptic spikes. The temporal order of spikes turned out to be crucial. We here take into account how propagation delays, composed of dendritic and axonal delay times, may affect the temporal order of spikes. In a minimal setting, characterized by neglecting dendritic and axonal propagation delays, STDP eliminates bidirectional connections between two coupled neurons and turns them into unidirectional connections. In this paper, however, we show that depending on the dendritic and axonal propagation delays, the temporal order of spikes at the synapses can be different from those in the cell bodies and, consequently, qualitatively different connectivity patterns emerge. In particular, we show that for a system of two coupled oscillatory neurons, bidirectional synapses can be preserved and potentiated. Intriguingly, this finding also translates to large networks of type-II phase oscillators and, hence, crucially impacts on the overall hierarchical connectivity patterns of oscillatory neuronal networks. |