This title appears in the Scientific Report :
2018
Please use the identifier:
http://hdl.handle.net/2128/18268 in citations.
Please use the identifier: http://dx.doi.org/10.1016/j.tics.2018.01.010 in citations.
How to Characterize the Function of a Brain Region
How to Characterize the Function of a Brain Region
Many brain regions have been defined, but a comprehensive formalization of each region's function in relation to human behavior is still lacking. Current knowledge comes from various fields, which have diverse conceptions of 'functions'. We briefly review these fields and outline how...
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Personal Name(s): | GENON, Sarah (Corresponding author) |
---|---|
Reid, Andrew / Langner, Robert / Amunts, Katrin / Eickhoff, Simon | |
Contributing Institute: |
Strukturelle und funktionelle Organisation des Gehirns; INM-1 Gehirn & Verhalten; INM-7 |
Published in: | Trends in cognitive sciences, 22 (2018) 4, S. 350-364 |
Imprint: |
Amsterdam [u.a.]
Elsevier Science
2018
|
PubMed ID: |
29501326 |
DOI: |
10.1016/j.tics.2018.01.010 |
Document Type: |
Journal Article |
Research Program: |
Human Brain Project Specific Grant Agreement 1 Connectivity and Activity |
Link: |
OpenAccess OpenAccess OpenAccess OpenAccess |
Publikationsportal JuSER |
Please use the identifier: http://dx.doi.org/10.1016/j.tics.2018.01.010 in citations.
Many brain regions have been defined, but a comprehensive formalization of each region's function in relation to human behavior is still lacking. Current knowledge comes from various fields, which have diverse conceptions of 'functions'. We briefly review these fields and outline how the heterogeneity of associations could be harnessed to disclose the computational function of any region. Aggregating activation data from neuroimaging studies allows us to characterize the functional engagement of a region across a range of experimental conditions. Furthermore, large-sample data can disclose covariation between brain region features and ecological behavioral phenotyping. Combining these two approaches opens a new perspective to determine the behavioral associations of a brain region, and hence its function and broader role within large-scale functional networks. |