This title appears in the Scientific Report :
2018
Please use the identifier:
http://dx.doi.org/10.1016/B978-0-444-63639-3.00024-4 in citations.
Cyto- and receptor architectonic mapping of the human brain.
Cyto- and receptor architectonic mapping of the human brain.
Mapping of the human brain is more than the generation of an atlas-based parcellation of brain regions using histologic or histochemical criteria. It is the attempt to provide a topographically informed model of the structural and functional organization of the brain. To achieve this goal a multimod...
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Personal Name(s): | Palomero-Gallagher, Nicola |
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Zilles, Karl (Corresponding author) | |
Contributing Institute: |
Strukturelle und funktionelle Organisation des Gehirns; INM-1 |
Published in: |
Brain Banking / Palomero-Gallagher, Nicola ; : Elsevier, 2018, ; ISSN: 00729752 ; ISBN: 9780444636393 ; doi:10.1016/B978-0-444-63639-3.00024-4 |
Imprint: |
Amsterdam [u.a.]
Elsevier
2018
|
Physical Description: |
355 - 387 |
PubMed ID: |
29496153 |
DOI: |
10.1016/B978-0-444-63639-3.00024-4 |
Document Type: |
Contribution to a book |
Research Program: |
Human Brain Project Specific Grant Agreement 1 Connectivity and Activity |
Edition: | 3rd series |
Series Title: |
Handbook of Clinical Neurology
150 |
Publikationsportal JuSER |
Mapping of the human brain is more than the generation of an atlas-based parcellation of brain regions using histologic or histochemical criteria. It is the attempt to provide a topographically informed model of the structural and functional organization of the brain. To achieve this goal a multimodal atlas of the detailed microscopic and neurochemical structure of the brain must be registered to a stereotaxic reference space or brain, which also serves as reference for topographic assignment of functional data, e.g., functional magnet resonance imaging, electroencephalography, or magnetoencephalography, as well as metabolic imaging, e.g., positron emission tomography. Although classic maps remain pioneering steps, they do not match recent concepts of the functional organization in many regions, and suffer from methodic drawbacks. This chapter provides a summary of the recent status of human brain mapping, which is based on multimodal approaches integrating results of quantitative cyto- and receptor architectonic studies with focus on the cerebral cortex in a widely used reference brain. Descriptions of the methods for observer-independent and statistically testable cytoarchitectonic parcellations, quantitative multireceptor mapping, and registration to the reference brain, including the concept of probability maps and a toolbox for using the maps in functional neuroimaging studies, are provided. |