This title appears in the Scientific Report :
2018
Apraxic deficits in sub-acute right hemisphere stroke result from deficient allo-centric visuo-spatial processing.
Apraxic deficits in sub-acute right hemisphere stroke result from deficient allo-centric visuo-spatial processing.
PB10. Apraxic deficits in sub-acute right hemisphere stroke resultfrom deficient allo-centric visuo-spatial processing.S.D. Ubben 1,*, G.R. Fink 1,2, S. Kaesberg 2, E. Kalbe 3, J. Kessler 2, S.Vossel 2,4, P.H. Weiss 1,2 (1 Research Centre Jülich, CognitiveNeuroscience, Institute of Neuroscience and...
Saved in:
Personal Name(s): | Ubben, S. D. |
---|---|
Fink, G. R. / Kaesberg, S. / Kalbe, E. / Kessler, J. / Vossel, S. / Weiss-Blankenhorn, Peter | |
Contributing Institute: |
Kognitive Neurowissenschaften; INM-3 |
Imprint: |
2018
|
Conference: | 31st International Congress of Clinical Neurophysiology (ICCN) of the IFCN, Washington (USA), 2018-05-01 - 2018-05-06 |
Document Type: |
Abstract |
Research Program: |
(Dys-)function and Plasticity |
Publikationsportal JuSER |
PB10. Apraxic deficits in sub-acute right hemisphere stroke resultfrom deficient allo-centric visuo-spatial processing.S.D. Ubben 1,*, G.R. Fink 1,2, S. Kaesberg 2, E. Kalbe 3, J. Kessler 2, S.Vossel 2,4, P.H. Weiss 1,2 (1 Research Centre Jülich, CognitiveNeuroscience, Institute of Neuroscience and Medicine (INM-3),Jülich, Germany, 2 University Hospital Cologne, Department ofNeurology, Köln, Germany, 3 University Hospital Cologne,Department of Medical Psychology, Köln, Germany , 4 Universityof Cologne, Department of Psychology, Köln, Germany)⇑ Presenting author.While visuo-spatial deficits are well characterized cognitivesequelae of right hemisphere (RH) stroke, apraxic deficits in RHstroke remain poorly understood. Likewise, very little is knownabout the association between apraxic and visuo-spatial deficits inRH stroke or about the putative common or differential pathophysiologyunderlying these deficits.Therefore, we examined the behavioral and lesion patterns ofapraxic deficits (pantomime of object use and bucco-facial imitation)and visuo-spatial deficits (line bisection and letter cancellationtasks) in 50 sub-acute RH stroke patients. Using principal componentanalysis (PCA), we characterized the relationship between the two deficits. We hypothesized that any interaction of these neuropsychologicalmeasures may be influenced by the demands of ego-centric/space-based and/or allo-centric/object-based processing.Contra-lesional visuo-spatial deficits were common in our clinicallyrepresentative patient sample, affecting more than half of RHstroke patients. Furthermore, about one third of all patients demonstratedapraxic deficits.PCA revealed that pantomiming and the imitation of bucco-facialgestures loaded clearly on a first component (PCA1), while lettercancellation loaded heavily on a second component (PCA2). For linebisection, overall mean deviation loaded on PCA1, while the differencebetween the mean deviations in contra- versus ipsi-lesionalspace loaded on PCA2.These results propose that PCA1 represents allo-centric/objectbasedprocessing and PCA2 2 ego-centric/space-based processing.This interpretation was corroborated by the statistical lesion analyseswith the component scores.Data suggest that apraxic pantomime and imitation deficits in RHstroke result, at least in part, from disturbed allo-centric/objectbasedprocessing. |