This title appears in the Scientific Report :
2019
Please use the identifier:
http://dx.doi.org/10.1111/jnc.14575 in citations.
Fingolimod (FTY720) is not protective in the subacute MPTP mouse model of Parkinson's disease and does not lead to a sustainable increase of brain-derived neurotrophic factor
Fingolimod (FTY720) is not protective in the subacute MPTP mouse model of Parkinson's disease and does not lead to a sustainable increase of brain-derived neurotrophic factor
Parkinson's disease (PD) is characterized by the loss of midbrain dopaminergic neurons and aggregates of α‐synuclein termed Lewy bodies. Fingolimod (FTY720) is an agonist of sphingosine‐1 phosphate receptors and an approved oral treatment for multiple sclerosis. Fingolimod elevates brain‐derive...
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Personal Name(s): | Komnig, Daniel |
---|---|
Dagli, Toruntay Cem / Habib, Pardes / Zeyen, Thomas / Schulz, Jörg B. / Falkenburger, Björn H. (Corresponding author) | |
Contributing Institute: |
Jara-Institut Quantum Information; INM-11 |
Published in: | Journal of neurochemistry, 147 (2018) 5, S. 678 - 691 |
Imprint: |
Oxford
Wiley-Blackwell
2018
|
PubMed ID: |
30152864 |
DOI: |
10.1111/jnc.14575 |
Document Type: |
Journal Article |
Research Program: |
(Dys-)function and Plasticity |
Publikationsportal JuSER |