ELASTIC REGISTRATION OF HIGH-RESOLUTION 3D PLI DATA OF THE HUMAN BRAIN
ELASTIC REGISTRATION OF HIGH-RESOLUTION 3D PLI DATA OF THE HUMAN BRAIN
We introduce a new approach for the elastic registration ofhigh-resolution 3D polarized light imaging (3D PLI) data ofhistological sections of the human brain. For accurate regis-tration of different types of 3D PLI modalities, we proposea novel intensity similarity measure that is based on a least-...
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Personal Name(s): | Sharib, Ali (Corresponding author) |
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Rohr / Axer, Markus / Grässel, David / Schlömer, Philipp / Amunts, Katrin / Eils / Wörz | |
Contributing Institute: |
Strukturelle und funktionelle Organisation des Gehirns; INM-1 |
Imprint: |
2017
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Physical Description: |
1-5 |
Conference: | IEEE International Symposium on Biomedical Imaging, Barcelona (Spain), 2017-04-18 - 2017-04-21 |
Document Type: |
Contribution to a conference proceedings |
Research Program: |
Supercomputing and Modelling for the Human Brain Human Brain Project Specific Grant Agreement 1 Connectivity and Activity |
Link: |
OpenAccess OpenAccess |
Publikationsportal JuSER |
We introduce a new approach for the elastic registration ofhigh-resolution 3D polarized light imaging (3D PLI) data ofhistological sections of the human brain. For accurate regis-tration of different types of 3D PLI modalities, we proposea novel intensity similarity measure that is based on a least-squares formulation of normalized cross-correlation. More-over, we present a fully automatic registration pipeline forrigid and elastic registration of high-resolution 3D PLI imageswith a blockface reference including a preprocessing step. Wehave successfully evaluated our approach using manually ob-tained ground truth for five sections of a human brain and ex-perimentally compared it with previous approaches. We alsopresent experimental results for 60 brain sections. |