This title appears in the Scientific Report :
2019
Please use the identifier:
http://dx.doi.org/10.1007/978-1-4939-8873-0_2 in citations.
Structural Studies of Autophagy-Related Proteins
Structural Studies of Autophagy-Related Proteins
Information about the structure and dynamics of proteins is crucial for understanding their physiological functions as well as for the development of strategies to modulate these activities. In this chapter we will describe the work packages required to determine the three-dimensional structures of...
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Personal Name(s): | Schwarten, Melanie |
---|---|
Weiergräber, Oliver H. / Petrović, Dušan / Strodel, Birgit / Willbold, Dieter (Corresponding author) | |
Contributing Institute: |
Strukturbiochemie; ICS-6 |
Published in: |
Autophagy / Ktistakis, Nicholas (Editor) Chapter 2 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-4939-8872-3=978-1-4939-8873-0 ; doi:10.1007/978-1-4939-8873-0 |
Imprint: |
New York, NY
Springer New York
2019
|
Physical Description: |
17 - 56 |
ISBN: |
978-1-4939-8872-3 (print) 978-1-4939-8873-0 (electronic) |
DOI: |
10.1007/978-1-4939-8873-0_2 |
PubMed ID: |
30610688 |
Document Type: |
Contribution to a book |
Research Program: |
Engineering Cell Function |
Series Title: |
Methods in Molecular Biology
1880 |
Publikationsportal JuSER |
Information about the structure and dynamics of proteins is crucial for understanding their physiological functions as well as for the development of strategies to modulate these activities. In this chapter we will describe the work packages required to determine the three-dimensional structures of proteins involved in autophagy by using X-ray crystallography or nuclear magnetic resonance (NMR) spectroscopy. Further we will provide instructions how to perform a molecular dynamics (MD) simulation using GABARAP as example protein. |