This title appears in the Scientific Report :
2021
Please use the identifier:
http://dx.doi.org/10.1093/brain/awaa417 in citations.
Please use the identifier: http://hdl.handle.net/2128/27399 in citations.
Reference values for the Cerebellar Cognitive Affective / Schahmann Syndrome Scale: Age and education matter
Reference values for the Cerebellar Cognitive Affective / Schahmann Syndrome Scale: Age and education matter
During recent decades, many studies have yielded evidence for cerebellar involvement in cognitive, emotional and affective processes besides the well-known cerebellar contribution to motor performance and learning (Koziol et al., 2014; Marien et al., 2014; Van Overwalle et al., 2014; Strata, 2015; A...
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Personal Name(s): | Thieme, A. (Corresponding author) |
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Röske, S. / Faber, J. / Sulzer, P. / Minnerop, Martina / Elben, S. / Jacobi, H. / Reetz, K. / Dogan, I. / Barkhoff, M. / Konczak, J. / Wondzinski, E. / Siebler, M. / Hetze, S. / Müller, O. / Sure, U. / Schmahmann, J. D. / Klockgether, T. / Synofzik, M. / Timmann, D. | |
Contributing Institute: |
Strukturelle und funktionelle Organisation des Gehirns; INM-1 |
Published in: | Brain, 144 (2021) 2, S. e20 |
Imprint: |
Oxford
Oxford Univ. Press
2021
|
DOI: |
10.1093/brain/awaa417 |
Document Type: |
Journal Article |
Research Program: |
Multilevel Brain Organization and Variability |
Link: |
Published on 2020-12-27. Available in OpenAccess from 2021-12-27. Restricted |
Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/27399 in citations.
During recent decades, many studies have yielded evidence for cerebellar involvement in cognitive, emotional and affective processes besides the well-known cerebellar contribution to motor performance and learning (Koziol et al., 2014; Marien et al., 2014; Van Overwalle et al., 2014; Strata, 2015; Adamaszek et al., 2017; Kansal et al., 2017; Guell et al., 2018; King et al., 2019). Cerebellar diseases can result in executive, linguistic and visuospatial dysfunctions as well as problems with the regulation of emotion and affect. This combination of non-motor symptoms has been named cerebellar cognitive affective/Schmahmann syndrome (CCAS) (Schmahmann and Sherman, 1998). For many years, diagnosis has relied on non-standardized bedside cognitive examination and, if available, detailed neuropsychological test batteries. A short and easily applicable bedside test (CCAS Scale), published by Hoche et al. (2018) in Brain, was developed to screen for CCAS and is already in widespread use. We therefore believe that it is important to share our recent findings that the reference values published by Hoche and colleagues may apply only within a limited age and education range, while their more universal application may lead to a substantial number of false-positive test results. |