This title appears in the Scientific Report :
2021
Please use the identifier:
http://dx.doi.org/10.1039/D1OB00279A in citations.
Please use the identifier: http://hdl.handle.net/2128/28581 in citations.
An artificial ruthenium-containing β-barrel protein for alkene–alkyne coupling reaction
An artificial ruthenium-containing β-barrel protein for alkene–alkyne coupling reaction
A modified Cp*Ru complex, equipped with a maleimide group, was covalently attached to a cysteine of an engineered variant of Ferric hydroxamate uptake protein component: A (FhuA). This synthetic metalloprotein catalyzed the intermolecular alkene–alkyne coupling of 3-butenol with 5-hexynenitrile. Whe...
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Personal Name(s): | Thiel, Andreas |
---|---|
Sauer, Daniel F. / Markel, Ulrich / Mertens, Stephanie / Polen, Tino / Schwaneberg, Ulrich / Okuda, Jun (Corresponding author) | |
Contributing Institute: |
Biotechnologie; IBG-1 |
Published in: | Organic & biomolecular chemistry, 19 (2021) 13, S. 2912 - 2916 |
Imprint: |
Cambridge
Royal Society of Chemistry
2021
|
DOI: |
10.1039/D1OB00279A |
PubMed ID: |
33735355 |
Document Type: |
Journal Article |
Research Program: |
Utilization of renewable carbon and energy sources and engineering of ecosystem functions |
Link: |
Published on 2021-03-15. Available in OpenAccess from 2022-03-15. Restricted |
Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/28581 in citations.
A modified Cp*Ru complex, equipped with a maleimide group, was covalently attached to a cysteine of an engineered variant of Ferric hydroxamate uptake protein component: A (FhuA). This synthetic metalloprotein catalyzed the intermolecular alkene–alkyne coupling of 3-butenol with 5-hexynenitrile. When compared with the protein-free Cp*Ru catalyst, the biohybrid catalyst produced the linear product with higher regioselectivity. |