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BioCyc is a collection of 18,030 Pathway/Genome Databases, plus software tools for exploring them. Key aspects of BioCyc data: - Quality data curated from tens of thousands of publications, including curated databases for E. coli, B. subtilis, S. cerevisiae, and H. sapiens - Computationally predicted metabolic pathways and operons (bacteria and archaea) - Data integrated from other databases including gene essentiality, regulatory networks, protein features, and GO annotations
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The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.
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ExPASy is the SIB Bioinformatics Resource Portal which provides access to scientific databases and software tools in different areas of life sciences including proteomics, genomics, phylogeny, systems biology, population genetics, transcriptomics etc.
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Tools for in silico experiments with complete genomes. The list of genomes and associated data are updated shortly after their availability at NCBI.
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KEGG is a database resource for understanding high-level functions and utilities of the biological system, such as the cell, the organism and the ecosystem, from molecular-level information, especially large-scale molecular datasets generated by genome sequencing and other high-throughput experimental technologies. Databases: - KEGG PATHWAY: Pathway information - KEGG GENES: Genomicinformation - KEGG LIGAND: Chemical information - KEGG BRITE: Binary relations and hierarchies etc.
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