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Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Aβ(1–42) Amyloid Fibrils

Becker, Nina
2023

Journal of the American Chemical Society, 145 (2023) 4, S. 2161–2169

“...Frieg, Benedikt...”

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Development of a First-in-Class Small-Molecule Inhibitor of the C-Terminal Hsp90 Dimerization

Bhatia, Sanil
2022

ACS central science, 8 (2022) 5, S. 636–655

“...Frieg, Benedikt...”

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Functional and structural characterization of interactions between opposite subunits in HCN pacemaker channels

Kondapuram, Mahesh
2022

Communications biology, 5 (2022) 1, S. 430

“...Frieg, Benedikt...”

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Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects

Gopalswamy, Mohanraj
2022

Scientific reports, 12 (2022) 1, S. 14158

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Aqueous ionic liquids redistribute local enzyme stability via long-range perturbation pathways

El Harrar, Till
2021

Computational and structural biotechnology journal, 19 (2021) S. 4248-4264

“...Frieg, Benedikt...”

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Binding Modes of Thioflavin T and Congo Red to the Fibril Structure of Amyloid-β(1–42)

Frieg, Benedikt
2020

Chemical communications, 56 (2020) S. 7589-7592

“...Frieg, Benedikt...”

Get full text Published on 2020-06-01. Available in OpenAccess from 2021-06-01. Published on 2020-06-01. Available in OpenAccess from 2021-06-01. Get full text

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Mechanism of fully-reversible, pH-sensitive inhibition of human glutamine synthetase by tyrosine nitration

Frieg, Benedikt
2020

Journal of chemical theory and computation, 16 (2020) 7, S. 4694–4705

“...Frieg, Benedikt...”

Get full text Published on 2020-06-17. Available in OpenAccess from 2021-06-17. Published on 2020-06-17. Available in OpenAccess from 2021-06-17. Get full text

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Small-molecule inhibitors of nisin resistance protein NSR from the human pathogen Streptococcus agalactiae

Porta, Nicola
2019

Bioorganic & medicinal chemistry, 27 (2019) 20, S. 115079

“...Frieg, Benedikt...”

Published on 2019-08-26. Available in OpenAccess from 2021-08-26. Published on 2019-08-26. Available in OpenAccess from 2021-08-26.

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Partially inserted nascent chain unzips the lateral gate of the Sec translocon

Kater, Lukas
2019

EMBO reports, 20 (2019) S. e48191

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Targeting HSP90 dimerization via the C-terminus is effective in imatinib resistant CML and lacks heat shock response

Bhatia, Sanil
2018

Blood, 132 (2018) 3, S. 307-320

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Journal Article 10

Frieg, Benedikt 10 Gohlke, Holger 10 Gopalswamy, Mohanraj 3 Smits, Sander H. J. 3 Bhatia, Sanil 2 Bickel, David 2 more ... Bopp, Bertan 2 Borkhardt, Arndt 2 Diedrich, Daniela 2 Etzkorn, Manuel 2 Gremer, Lothar 2 Groth, Georg 2 Hansen, Finn K. 2 Hauer, Julia 2 Heise, Henrike 2 Jose, Joachim 2 Kurz, Thomas 2 Lang, Franziska 2 Nagel-Steger, Luitgard 2 Reiners, Jens 2 Willbold, Dieter 2 Aghaallaei, Narges 1 Ahlert, Heinz 1 Akter, Shahina 1 Babor, Florian 1 Bajohgli, Baubak 1 Becker, Nina 1 Beckmann, Roland 1 Benndorf, Klaus 1 Berninghausen, Otto 1 see all ... less ...

Forschergruppe Gohlke Biological and environmental resources for sustainable use 5 Computational Science and Mathematical Methods 5 Domain-Specific Simulation & Data Life Cycle Labs (SDLs) and Research Groups 5 Molecular Information Processing in Cellular Systems 3 Physical Basis of Diseases 2 more ... Biological Key Regulators and Small Chemical Compounds 1 Center for Simulation and Data Science (CSD) - School for Simulation and Data Science (SSD) 1 Disease Mechanisms 1 Infections and cancer 1 Information Processing in Neuronal Networks 1 Utilization of renewable carbon and energy sources and engineering of ecosystem functions 1 see all ... less ...

John von Neumann - Institut für Computing; NIC 10 Jülich Supercomputing Center; JSC 10 Strukturbiochemie; IBI-7 7 Bioinformatik; IBG-4 5 Strukturbiochemie; ICS-6 3 Institut für Molekulare Enzymtechnologie (HHUD); IMET 1

2022 3 2019 2 2020 2 2018 1 2021 1 2023 1

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