Stem Cell-Derived Models in Toxicology [E-Book] / edited by Mike Clements, Liz Roquemore.
This detailed volume brings together a diverse collection of stem cell-derived model-based toxicity assays, from those routinely used to those deemed to have considerable potential. With a focus on differentiated tissues, the chapters explore numerous cardiotoxicity applications as well as coverage...
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Full text |
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Personal Name(s): | Clements, Mike, editor |
Roquemore, Liz, editor | |
Imprint: |
New York, NY :
Humana Press,
2017
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Physical Description: |
XII, 341 p. 124 illus., 108 illus. in color. online resource. |
Note: |
englisch |
ISBN: |
9781493966615 |
DOI: |
10.1007/978-1-4939-6661-5 |
Series Title: |
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Methods in pharmacology and toxicology
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- Stem CellDerived Models for Safety and Toxicity Assessments: Present and Future Studies in the Proclinical Space
- Human Pluripotent Stem Cell Test for Assessing the Potential Teratogen Risk
- Cardiac Action Potential Measurement in Human Embryonic Stem Cell Cardiomyocytes for Cardiac Safety Studies Using Manual Patch-Clamp Electrophysiology
- Automated Patch Clamp Recordings of Human Stem Cell-Derived Cardiomyocytes
- The CiPA Microelectrode Array Assay with hSC-Derived Cardiomyocytes: Current Protocol, Future Potential
- Optogenetic Approach to Cardiotoxicity Screening: Simultaneous Voltage and Calcium Imaging Under Paced Conditions
- HTS Compatible Voltage- and Ca2+-Sensitive Dye Recordings from hiPSC-Derived Cardiomyocytes Using the Hamamatsu FDSS Systems
- Kinetic Image Cytometry for Predicting Arrhythmias Using Human Stem Cell-Derived Cardiomyocytes
- Decoding Ca2+ Signals as a Non-Electrophysiological Method for Assessing Drug Toxicity in Stem-Cell Derived Cardiomyocytes
- Combined Impedance and Extracellular Field Potential Recordings from Human Stem Cell-Derived Cardiomyocytes
- Edge Detection for Contractility Measurements with Cardiac Spheroids
- Contractile Force Readout of hESC-Cardiomyocytes
- In Vitro Cardiotoxicity Investigation Using High Content Analysis and Human Stem Cell-Derived Models
- Structural Toxicity: Hypertrophy Models of Human Pluripotent Stem Cell-Derived Cardiomyocytes
- Addressing Functional Neurotoxicity Using the Microelectrode Array (MEA)
- Micropatterned Co-Cultures of Induced Pluripotent Stem Cell-Derived Hepatocytes and Stromal Cells for Drug Toxicity Studies.