Smart materials for tissue engineering [E-Book] / editor: Qun Wang.
In recent years there has been tremendous progress in the area of tissue engineering research. This book focusses on the fundamental principles underpinning these recent advances in the materials science developed for tissue engineering purposes. Smart materials for tissue engineering are produced b...
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Full text |
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Personal Name(s): | Wang, Qun, editor |
Imprint: |
[Cambridge] :
Royal Society of Chemistry,
[2017]
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Physical Description: |
1 online resource. |
Note: |
englisch |
ISBN: |
9781782626756 1782626751 |
Series Title: |
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Smart materials series ;
24 |
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Classification: |
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082 | 0 | 4 | |a 610.28 |2 23 |
084 | 0 | |a HCE - Biomedical engineering - general aspects | |
084 | 0 | |a LRR - Tissue cultures, cell cultures | |
245 | 0 | 0 | |a Smart materials for tissue engineering |h [E-Book] / |c editor: Qun Wang. |
264 | 1 | |a [Cambridge] : |b Royal Society of Chemistry, |c [2017] |e (RSC) |f RSC20170119 | |
300 | |a 1 online resource. | ||
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490 | |a Smart materials series ; |v 24 | ||
500 | |a englisch | ||
505 | 0 | |a Cover; Smart Materials for Tissue Engineering: Fundamental Principles; Foreword; Preface; Contents; Chapter 1 -- Smart Design of Materials for Tissue Engineering; 1.1 Introduction; 1.2 Mechanism Underlying Interaction of Cells with the Extracellular Matrix; 1.2.1 Direct Physical Signal Transmission Pathway; 1.2.2 Indirect Mechanochemical Signal Transduction Pathway; 1.2.3 Control of Cell Differentiation, Proliferation, and Migration by Defining the Dynamics of the Cell Adhesion Complex and Act...; 1.2.3.1 Stem Cell Differentiation; 1.2.3.2 Cell Proliferation; 1.2.3.3 Cell Migration | |
505 | 8 | |a 1.3 Determinants of Cell Fate in the Extracellular Matrix1.3.1 Composition of Cell Adhesion Proteins; 1.3.2 ECM Topography; 1.3.3 ECM Stiffness; 1.4 Spatial and Temporal Scales in Cell and Material Interactions; 1.4.1 Molecular Level: Integrin; 1.4.2 Molecular Assembly Level; 1.4.2.1 Integrin Cluster; 1.4.2.2 Actin Cytoskeleton; 1.4.3 Single-Cell Level; 1.4.4 Multiple-Cell Level; 1.4.5 Integration of Multiple Spatiotemporal Effects; 1.5 Smart Design of Materials to Control the Dynamic State of Tissues; 1.6 Future Challenges; Acknowledgements; References | |
505 | 8 | |a 2.4.5 Multi-Modal Delivery2.4.6 Scaffolds for Bone Tumor Destruction; 2.5 Concluding Remarks and Perspectives; References; Chapter 3 -- Protein-Based Stimuli Responsive Materials for Tissue Engineering; 3.1 Stimuli Responsiveness; 3.2 Types of Stimuli Responsiveness; 3.2.1 Temperature Responsiveness; 3.2.2 Electrical Responsiveness; 3.2.3 Light Responsiveness; 3.2.4 pH Responsive; 3.2.5 Redox Responsiveness; 3.2.6 Ion-Responsive Polymers; 3.2.7 Glucose Responsiveness; 3.2.8 Enzyme-Responsive Polymers; 3.3 Types of Polymeric Stimuli-Responsive Structures; 3.3.1 Hydrogels; 3.3.2 Micelles | |
505 | 8 | |a 3.3.3 Dendrimers3.3.4 Nanoparticles; 3.4 Protein-Based Responsive Systems; 3.5 Application in Tissue Engineering; 3.6 Conclusions and Future Perspectives; Acknowledgements; References; Chapter 4 -- Stimuli-Responsive Hydrogels for Tissue Engineering; 4.1 Introduction; 4.2 The Properties of Hydrogels for Tissue Engineering; 4.2.1 Mechanical Properties of Hydrogels; 4.2.2 Surface Chemistry of Hydrogels; 4.2.3 Biocompatibility and Biodegradability of Hydrogels; 4.2.4 Electrical Properties of Hydrogels; 4.3 Stimuli-Responsive Hydrogels; 4.3.1 Natural-Based Smart Hydrogels; 4.3.1.1 Chitosan | |
505 | 8 | |a Chapter 2 -- Smart Surfaces Chemistry and Coating Materials for Tissue Engineering2.1 Introduction; 2.1.1 Tissue Engineering and Scaffolds; 2.1.2 Cell-EMC Interaction via Integrin and Surface Topography; 2.2 RGD Nanospacing; 2.2.1 Nanospacing in 2-D Substrates with Different Stiffness; 2.2.2 3-D Substrates; 2.3 Surface Topography-Mediated Stem Cell Fate; 2.4 Scaffold-Mediated Gene Delivery by Biomimetic Coating; 2.4.1 Gene-Transfer; 2.4.2 DNA/CP Complex as a Drug-Delivery System by Biomimetic Coating; 2.4.3 Polyplexes as Drug-Delivery Systems; 2.4.4 Targeting the Nucleus | |
520 | |a In recent years there has been tremendous progress in the area of tissue engineering research. This book focusses on the fundamental principles underpinning these recent advances in the materials science developed for tissue engineering purposes. Smart materials for tissue engineering are produced by modifying the physicochemical and biological properties of the scaffolds with response to external stimuli to enhance the tissue regeneration. The functions of living cells can be regulated by smart materials which respond to changes in the surrounding microenvironment. This book comprehensively documents the recent advancements in smart materials for tissue engineering and will provide an essential text for those working in materials science and materials engineering, in academia and industry. | ||
650 | 0 | |a Biomedical materials. | |
650 | 0 | |a Smart materials. | |
650 | 0 | |a Tissue engineering. | |
650 | 4 | |a biomaterial | |
650 | 4 | |a biomedical engineering | |
650 | 4 | |a tissue | |
700 | 1 | |a Wang, Qun, |e editor | |
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