Molecular Diversity in Drug Design [E-Book] / edited by Philip M. Dean, Richard A. Lewis.
High-throughput screening and combinatorial chemistry are two of the most potent weapons ever to have been used in the discovery of new drugs. At a stroke, it seems to be possible to synthesise more molecules in a month than have previously been made in the whole of the distinguished history of orga...
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Full text |
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Personal Name(s): | Dean, Philip M., editor |
Lewis, Richard A., editor | |
Imprint: |
Dordrecht :
Springer Netherlands,
2002
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Physical Description: |
XIV, 254 p. online resource. |
Note: |
englisch |
ISBN: |
9780306468735 |
DOI: |
10.1007/0-306-46873-5 |
Subject (LOC): |
- Issues in Molecular Diversity and the Role of Ligand Binding Sites
- Molecular Diversity in Drug Design. Application to High-speed Synthesis and High-Throughput Screening
- Background Theory of Molecular Diversity
- Absolute vs Relative Similarity and Diversity
- Diversity in Very Large Libraries
- Subset-Selection Methods For Chemical Databases
- Molecular Diversity in Site-focused Libraries
- Managing Combinatorial Chemistry Information
- Design of Small Libraries for Lead Exploration
- The Design of Small- and Medium-sized Focused Combinatorial Libraries.