Alzheimer's Disease [E-Book] : Methods and Protocols / edited by Jerold Chun.
This volume explores the latest techniques used to study the human brain towards understanding Alzheimer's Disease and related neurodegenerative disorders. Contributed to by world-renowned experts, the chapters in this book are divided into five parts. Part One discusses human post-mortem brain...
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Full text |
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Personal Name(s): | Chun, Jerold, editor |
Edition: |
1st edition 2023. |
Imprint: |
New York, NY :
Humana Press,
2023
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Physical Description: |
XIII, 340 pages 61 illustrations, 59 illustrations in color (online resource) |
Note: |
englisch |
ISBN: |
9781071626559 |
DOI: |
10.1007/978-1-0716-2655-9 |
Series Title: |
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Methods in Molecular Biology ;
2561 |
Subject (LOC): |
This volume explores the latest techniques used to study the human brain towards understanding Alzheimer's Disease and related neurodegenerative disorders. Contributed to by world-renowned experts, the chapters in this book are divided into five parts. Part One discusses human post-mortem brain preparations including single-cell isolation and use of specialized imaging. Part Two talks about neural cellular models using primary and human induced pluripotent stem cells to model aspects of the human brain. Part Three details nucleic acid analyses including transcriptomic and somatic genomic changes, and Part Four discusses lipid analyses via mass spectrometry. Lastly, Part Five covers protein analyses, particularly Aβ and Tau. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Alzheimer's Disease: Methods and Protocols is a valuable tool for all researchers who want to expand their knowledge and understanding of this disease and other related dementias. |