Theory of Coherent and Incoherent Nuclear Spin Dephasing in the Heart
Bauer, Wolfgang (Corresponding Author)
Nadler, Walter / Bock, Michael / Schad, Lothar / Wacker, Christian / Hartlep, Andreas / Ertl, Georg
John von Neumann - Institut für Computing; NIC
Physical review letters, 83 (1999) 20, S. 4215 - 4218
College Park, Md. APS 1999
Journal Article
ohne Topic
Please use the identifier: in citations.
Please use the identifier: in citations.
We present an analytical theory of susceptibility induced nuclear spin dephasing in the capillary network of myocardium. Using a strong collision approach, equations are obtained for the relaxation rate of the free induction and the spin echo decay. Simulation and experimental data are well predicted by the theory. Since paramagnetic deoxyhemoglobin as the origin of nuclear spin dephasing has a higher tissue concentration in myocardium supplied by a stenotic, i.e., significantly narrowed, coronary artery, spin dephasing might serve as a diagnostic tool. Our approach can be modified for capillary networks in other tissues than myocardium and may be applied in material science.