This title appears in the Scientific Report : 2015 

QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers

QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers

Strong evidence exists for a central role of amyloid β-protein (Aβ) oligomers in the pathogenesis of Alzheimer’s disease. We have developed a fast, reliable and robust in vitro assay, termed QIAD, to quantify the effect of any compound on the Aβ aggregate size distribution. Applying QIAD, we studied...

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Personal Name(s):	Brener, Oleksandr
	Dunkelmann, Tina / Gremer, Lothar / van Groen, Thomas / Mirecka, Ewa A. / Kadish, Inga / Willuweit, Antje / Kutzsche, Janine / Jürgens, Dagmar / Rudolph, Stephan / Tusche, Markus / Bongen, Patrick / Pietruszka, Jörg / Oesterhelt, Filipp / Langen, Karl-Josef / Demuth, Hans-Ulrich / Janssen, Arnold / Hoyer, Wolfgang / Funke, Susanne A. / Nagel-Steger, Luitgard / Willbold, Dieter (Corresponding author)
Contributing Institute:	Biotechnologie; IBG-1 Institut für Bioorganische Chemie (HHUD); IBOC Strukturbiochemie; ICS-6
Published in:	Scientific reports, 5 (2015) S. 13222
Imprint:	London Nature Publishing Group 2015
DOI:	10.1038/srep13222
PubMed ID:	26394756
Document Type:	Journal Article
Research Program:	Biotechnology Physical Basis of Diseases
Link:	Get full text OpenAccess OpenAccess
	Publikationsportal JuSER

Please use the identifier: http://dx.doi.org/10.1038/srep13222 in citations.
Please use the identifier: http://hdl.handle.net/2128/9555 in citations.